- Pharmaceutical intermediates
- Agricultural intermediates and concentrates
- Functional materials
- Special reactive agents
- Organometallic compounds
- Reactions using organao-silyl compounds or organic boron compounds
- Reduction using NaBH4, DIBAL-H etc.
- Metalation using BuLi, NaH etc.
- Alkylation-related reactions
- Chlorination using Cl2
- Esterification and trans-esterification
- Amidation and oximation
- Etherification
- Hydrolysis and dehydro-condensation
- Friedel-Crafts reaction
- Friedel-Crafts reaction2, Br2 etc.
- Reactions using hydrogen chloride
- Reactions using sulfur compounds
- Oxidation
- Oxidation
- Reaction vessels : 150 L ? 12,000 L
- Reaction vessel materials : GL, Ti, sus304, sus316
- Reaction temperatures : -30℃ ? 180℃
- Pressurized filter
- Centrifuge
- Vacuum dryer
- Vacuum distiller etc.

















Since 1958, when for the first time in Japan Nitto Kasei operated a large-scale Grignard reaction unit, the company has manufactured a wide variety of chemicals, including organic tin compounds, organao-silyl compounds, organometallic compounds and organic fine chemicals. Of all its manufacturing processes, Nitto Kasei excels most in the Grignard reaction, backed by over 50 years’ experience of industrial production and accumulated know-how.
Nitto Kasei’s R&D, manufacturing and quality assurance divisions work together in strong alliance, using organic synthetic technology based on the Grignard reaction and organometallic chemistry, providing customers with useful cooperation from the developmental stage. As a result, Nitto Kasei promptly realizes economically efficient processes that resolve customer problems and fulfill their needs.