Custom-made products

It was in 1958 that Nitto kicked off the operations of a large-scale Grignard reaction facility. Ever since, Nitto has manufactured a variety of organotin compounds, organometallic compounds and organic fine chemicals.
These technologies utilizing the Grignard reaction have become one of the best skills through rich experiences within four decades.
Furthermore Nitto Kasei has focussed on studying newer area by our favorite skills.
Nitto Kasei accepts orders of custom-made products from R&D scale to a large amount by using our technique.

Performance of Products

We can produce pharmaceutical intermediates in accordance with GMP , and we are pleased to cooperate actively in such cases as the joint development and business as to another fields.

Performance of reaction

Since Nitto has the knowledge accumulated by the key technology of Grignard reaction for about 40 years, Nitto can make the most of various organic synthetic technology.

Reduction (using NaBH4, (i-Bu)2AlH, etc.)
Metalation (using BuLi, NaH, etc.)
Alkylation-related reactions
Various condensation reactions
Chlorination (using Cl2 and SOCl2)
Friendel-Crafts reaction
Esterification and transesterification
Amidation
Etherification
Hydrolysis

Typical facilities and equipment←←←Click here!